NanoPhotometer® N60
Nucleic Acid & Protein UV-Assay Measurements | Built-in Vortex
Starting at 0.3 µl | Scan Range 200 – 900 nm
Features
- Broad Detection Range
dsDNA: 1 – 16,500 ng/µl | BSA: 0.03 – 478 mg/ml - Built-in Vortex* – Low vibration and low energy vortex
- Standalone or Remote Operated – Windows, Mac, Android, and iOS
- Portable with Battery Option – Only 20 x 20 x 12 cm footprint
- 5-Star Customer Support – Live application support 24/5
- GMP, GLP, GxP Ready 21 CFR Part 11 and IQOQ option
- No maintenance and recalibration required ever
Benefits
- Saves time and avoids manual dilution errors
- Ready for pharmaceutical applications and full dynamic range (e.g., for OD600 readings)
- Zero cost of ownership
- Flexible unit control and access to data from anywhere
- Ready to go into a glove box, under the hood, from lab bench to lab bench, or into the field
- Expert knowledge when you need it
- Full laboratory compliance with peace of mind
Preprogrammed Methods & Features
- Nucleic Acids (DNA, RNA, mRNA, Oligos, etc.) with QC Ratios (260/280 and 260/230)
- Protein UV with QC Ratio (260/280)
- Measure fluorescent dye-labeled Nucleic Acids and Proteins using absorbance
- Potential contaminant identification
- Further Life Science applications: OD600, Protein Assays (Bradford, BCA, Biuret), Kinetics in a drop
- UV-Vis Spectroscopy applications: Wavelength (including formula editor), Wavescan, Standard Curve, Concentration, Absorbance Ratio
“Awesome machine. I would purchase another one for additional labs.”
Rating: 5.0 ★★★★★
“I love the dynamic range for RNA/DNA measurements. We did our own in house check for reproducibility. The interface is very user friendly and easier to use than … We like that we can use 1 ul of precious sample for an accurate reading rather than the required 1.5ul for … I am in the midst of uploading the newest upgraded software so I will test it out and give additional feedback.
This has been a god-send. We have very low concentration samples that are very precious and this allows us to make measurements on these types of samples. Also, after doing PCR amplification, we no longer have to make dilutions for the upper limit readings due to the large dynamic range.
Twyla Juehne, Organization: Washington University School of Medicine, USA
N60: Best-in-Class Microvolume Spectrophotometer
The NanoPhotometer® N60 is a high-performance, portable UV/Vis spectrophotometer designed for microvolume spectroscopy, nucleic acid quantification, protein analysis, and a wide range of UV/Vis spectroscopy applications. Featuring a glove-compatible 7-inch touchscreen, flexible unit controls, and an integrated vortex mixer for improved sample uniformity, it delivers highly accurate results from sample volumes as small as 0.3 µL. An illuminated quartz sample surface simplifies sample loading, making measurements fast, easy, and reliable.
Mobile Design
Take microvolume spectroscopy wherever your work takes you. The N60 UV/Vis spectrophotometer features an ultra-compact 20 × 20 × 12 cm footprint and weighs just 3.8 to 5 kg, depending on the configuration, making it one of the most portable instruments in its class.
For maximum flexibility, an optional built-in battery pack provides up to 8 hours of standalone operation, enabling reliable UV/Vis spectroscopy measurements in the laboratory, at the bench, or in the field.
Compact & Stand-Alone
No computer required. Built-in computer with high-performance Intel Celeron dual-core 2.4 GHz processor and 64 GB of onboard memory provide powerful and easy storage of methods and data. Preprogrammed UV/Vis spectrophotometer applications are available for nucleic acid quantitation and purity check using the 260/280 and 260/230 ratio (dsDNA, ssDNA, RNA, mRNA, miRNA, oligos including dye-labeled samples), as well as for protein quantitation and purity check using the 260/280 ratio (BSA, antibodies, IgG, IgE, Serum Albumin, etc., including dye-labeled samples), small molecules in organic solvents, kinetics, and more.
Accurate Spectroscopy
Sample Compression Technology™ delivers exceptional precision and accuracy for UV/Vis spectrophotometer measurements, even with challenging samples such as proteins. By creating a stable capillary film between two quartz surfaces, it eliminates dependence on surface tension and prevents sample evaporation, ensuring consistent and reliable measurement conditions.
This innovative technology provides accurate nucleic acid and protein quantification, dependable 260/280 and 260/230 purity assessments, and supports a wide range of spectroscopy applications, including kinetic measurements in microvolume samples. The result is greater confidence in every measurement, from routine analysis to advanced research workflows.
Built-in Vortex Mixer
Achieve sample uniformity by vortexing prior to each measurement with the proprietary built-in NanoPhotometer® N60 low-vibration/low-energy vortexer for gentle mixing of even delicate samples; obtain readings that represent the accurate concentration of the entire sample.
Certainty in Real Time
Sample Control™ is an advanced quality control technology for UV/Vis spectrophotometers that automatically detects air bubbles, sample impurities, turbidity, lint residue, and potential contamination. It also supports real-time sample quality assessment through 260/280 and 260/230 ratio measurements, helping ensure reliable nucleic acid and protein analysis.
By continuously monitoring sample integrity and handling characteristics during measurement, Sample Control™ improves data quality, reproducibility, and confidence in concentration results, delivering the highest level of accuracy for microvolume applications.
Endless Connectivity
Equipped with Wi-Fi, built-In HotSpot, LAN, HDMI and USB A/B interface connections for remote instrument control, data accessibility, and printing. NPOS now supports AirPrint/IPP-compatible printers for PDFs, printers compatible with the HP universal driver, and DYMO label printers (cryo and standard labels). The NanoPhotometer® is compatible with 1D and 2D barcode readers, allowing for flexible and streamlined data entry. Unique file server functionality allows access of data stored on the NanoPhotometer® drive from any computer accessing the lab network.
Universal Data Output
Every NanoPhotometer® is able to generate formatted Excel and PDF document files for data processing or archiving of measurements on the lab network. The capability to print full page reports, labels, and cryo labels via USB and through a network connection lends users the utmost flexibility for data output. Supported printers include AirPrint/IPP-compatible printers for PDFs, printers with HP universal printer driver capability, and DYMO label printers.
AirPrint® is a registered trademark of Apple Inc. Cupertino, CA
Flexible Unit Control
Mobile and easy control of the NanoPhotometer® is possible via Wi-Fi from tablets or smartphones (Android OS & iOS). Easy control from PCs (Windows & Mac) is also available, with fast and flexible connection options including Wi-Fi, USB, and LAN.
Ultimate Data Security
Malware, viruses, and ransomware are serious threats to instrumentation operating on Android- or Windows-based platforms. The proprietary NanoPhotometer® Operating System NPOS protects data in a secure environment immune to known malicious software.
Whether running apps on the NanoPhotometer®/control device or downloading precious measurement results, your data is safe. For additional security the NanoPhotometer® does not allow browsing on the internet whilst providing safe access to control devices like computers, tablets, and smartphones.
CFR21 Software
The Implen CFR21 software supports FDA 21 CFR Part 11 compliance and is an optional software tool ideal for GxP laboratories, which require proper electronic record-keeping for UV/Vis spectroscopic measurements utilizing a microvolume or cuvette UV/Vis spectrophotometer. It includes user management, access control, electronic signatures, data integrity, security, and audit trail functionality.
Fast & Maintenance-Free Spectrophotometer
Turn on and instantly measure without lamp warm-up time. Full scan capability ranges from 200-900 nm for rapid and complete sample analysis in as little as 2.5 seconds. True Path Technology™ covers the extensive dynamic range with two precisely defined path lengths. The sealed mechanical setup has two fixed anchor points that remain unchanged over the lifetime of the instrument. No recalibration is necessary – Implen guarantees lifetime accuracy.
Confidence with Blank Control™
Be sure that your data are precise with Implen’s unique Blank Control™ feature for UV/Vis spectrophotometers. Blanks with high background or residue from previous samples are a major source of measurement inaccuracies. Blank Control™ prevents you from wasting time and precious samples on inaccurate readings caused by high background blanks or improper cleaning.
Universal Language Support
The NPOS user interface is offered in a selection of languages. The advanced language functionality allows the operator to effectively understand and interact with the unit, boosting productivity in the lab. In addition to a multilingual user interface, the NanoPhotometer® provides the flexibility to print results in multiple languages, which prevents misinterpretation of data and time-consuming translations.
The selection covers most widely spoken languages including English, Chinese, French, German, Japanese, Portuguese, Russian, and Spanish, and will be continuously extended.
Fun for Spectroscopy Nerds: The NanoPhotometer® Crew
Get to know the NanoPhotometer® Crew – the dedicated team behind reliable UV/Vis spectrophotometry for researchers worldwide. Follow their entertaining adventures as they work tirelessly to deliver accurate nucleic acid and protein quantification, dependable purity assessments (260/280 and 260/230 ratios), and precise results across a wide range of UV/Vis applications.
Their mission has been captured on video and is available directly on your instrument through the screensaver feature, included with firmware version 4.3 and later. Activate the screensaver and enjoy a behind-the-scenes look at the crew’s ongoing commitment to scientific excellence.
NanoPhotometer® N60 Tech Specs
Microvolume Spectrophotometer | 0.3 µl | Scan Range 200 – 900 nm
General Specifications
Dimensions: 20 cm x 20 cm x 12 cm
Weight: 3.8 – 5.2 kg depending on configuration
Processing Power/Software
- Linux based NPOS
- Intel Celeron dual core 2.4 GHz
- 64 GB Internal Data Storage
- 2x USB A, USB B
- HDMI, Ethernet, WiFi
- Windows 8, 10, 11 (32 & 64 bit)
- OS X (Intel x86 and Apple M1)
- iOS and Android OS
Display
- 1024 x 600 pixels
- Glove compatible touchscreen
Built-in Battery Pack
Optional rechargeable lithium ion battery
95 Wh, 6.6 Ah, 8 h
Min. charging cycles: 800
NanoVolume
Performance
| Detection Range dsDNA | 1 – 16,500 ng/µl |
| Detection Range BSA | 0.03 – 478 mg/ml |
| Minimum Sample Size | 0.3 – 2 µl |
| Photometric Range (10 mm equivalent) | 0.02 – 330 A |
| Path Length | 0.67 and 0.07 mm |
| Dilution Factor | 15 and 140 |
| Vortex | 2,800 rpm; tube size up to 2.0 ml |
Optical
Specifications
| Wavelength Scan Range | 200 – 900 nm |
| Measure Time For Full Scan Range | 2.5 – 4 seconds |
| Wavelength Reproducibility | ± 0.2 nm |
| Wavelength Accuracy | ± 0.75 nm |
| Bandwidth | < 1.5 nm |
| Absorbance Reproducibility | (Lid 15): < 0.002 A @ 0 – 0.3 A @ 280 nm CV < 1% @ 0.3 – 1.7 A @ 280 nm |
| Absorbance Accuracy | < 1.75% @ 0.7 A @ 280 nm of the reading |
| Stray Light | < 0.5% @ 240 nm using NaI |
| Optical Arrangement | 1 x 4096 CMOS Array |
| Lamp | Xenon flash lamp |
| Lifetime | 109 flashes, up to 10 years |
General
Specifications
| Operating Voltage | 90 – 250 V ± 10%, 50/60 Hz, 90 W, 18/19 VDC |
| Certification | CE, IEC 61010-1:2012 and EN 61326-1:2013 |
| Battery Certification | N60: IEC 62133 and UN38.3 transport test |
| Security | Slot for Kensington lock |
